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 SOX9
Homo sapiens
 HIF1A
Homo sapiens
 Pax6
Mus musculus
 PAX6
Homo sapiens
 Snai2
Mus musculus
 PPARA
Homo sapiens
 Ppara
Mus musculus
 Thrb
Mus musculus
 SNAI2
Homo sapiens
 Tbr1
Mus musculus
Transcription Factor Encyclopedia  BETA
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Genetics
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MeSH cloud (automatically populated)
About this section
The MeSH cloud below displays MeSH terms that are associated with this transcription factor. The physical size of the terms reflect the significance of their association with the transcription factor as determined by the Fisher's Exact Test. It should be noted that these associations do not necessarily imply a positive correlation between the described MeSH term and this transcription factor. For instance, if the MeSH term "apoptosis" occurs, it may indicate that this transcription factor can induce apoptosis (positive correlation), or prevent apoptosis (negative correlation). Methods: The transcription factor is mapped to a set of Pubmed publications through the gene-to-pubmed association as provided by NCBI. Then, a collection of MeSH terms associated with the papers are compiled, along with the frequency of each MeSH term. The Fisher's Exact Test is conducted on the frequency of each term in the collection, versus its average frequency, to determine its significance in the collection. More information on MeSH can be found on the MeSH homepage.
MeSH term Fisher's exact p-value
1 Atherosclerosis 2.3 x 10-7
2 Gallstones 1.0 x 10-5
3 Acute-Phase Reaction 9.0 x 10-5
4 Carcinoma, Hepatocellular 9.7 x 10-5
5 Insulin Resistance 0.00072
6 Adenoma, Liver Cell 0.0024
7 Drug-Induced Liver Injury 0.0048
8 Cholangiocarcinoma 0.017
9 Fibrosis 0.017
10 Hepatomegaly 0.024
11 Genetic Predisposition to Disease 0.031
12 Liver Cirrhosis, Biliary 0.031
13 Hypothermia 0.038
MeSH term Fisher's exact p-value
1 Biliary Tract Diseases 1.3 x 10-10
2 Atherosclerosis 2.3 x 10-7
3 Cholestasis 3.1 x 10-7
4 Cholelithiasis 6.6 x 10-7
5 Digestive System Diseases 1.5 x 10-6
6 Liver Diseases 3.3 x 10-6
7 Bile Duct Diseases 6.0 x 10-6
8 Gallstones 1.0 x 10-5
9 Cholecystolithiasis 1.1 x 10-5
10 Arteriosclerosis 1.8 x 10-5
11 Acute-Phase Reaction 9.0 x 10-5
12 Carcinoma, Hepatocellular 9.7 x 10-5
13 Arterial Occlusive Diseases 0.00012
14 Dyslipidemias 0.00018
15 Liver Neoplasms 0.00021
16 Inflammation 0.00036
17 Gallbladder Diseases 0.00052
18 Insulin Resistance 0.00072
19 Lipid Metabolism Disorders 0.00075
20 Hyperinsulinism 0.0010
21 Cholestasis, Intrahepatic 0.0011
22 Calculi 0.0015
23 Hyperlipidemias 0.0022
24 Adenoma, Liver Cell 0.0024
25 Drug-Induced Liver Injury 0.0048
26 Digestive System Neoplasms 0.013
27 Cholangiocarcinoma 0.017
28 Fibrosis 0.017
29 Disease Models, Animal 0.021
30 Hepatomegaly 0.024
31 Genetic Predisposition to Disease 0.031
32 Adenocarcinoma 0.031
33 Liver Cirrhosis, Biliary 0.031
34 Metabolic Diseases 0.037
35 Hypothermia 0.038
36 Glucose Metabolism Disorders 0.041
MGI mammalian phenotype terms (automatically populated)